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New Treatments Better Manage Traumatic Brain Injury

New research shows inhibiting certain enzymes decreases the severity of traumatic brain injury (TBI), providing a target for future treatments.  This research was published July 19th in the Brain.  Traumatic brain injury (TBI) is most often caused by a blow to the head sustained in a fall, car or truck accident, or any other accident.

Professor Medcalf said the researchers identified two enzymes, known as t-PA and MMP-3, that act together to promote injury severity following TBI.

“The enzyme t-PA, well known for its ability to remove blood clots, also has a healthy and very important role in supporting learning and memory functions in everyday life. However, previous research has shown that in TBI cases, its presence makes the injury much worse,” Professor Medcalf said.

t-PA was once thought to worsen the injury, but its inhibition triggers the activation of MMP-3, the enzyme which does the damage.

“The activity of naturally occurring enyzmes is controlled by specific enzyme inhibitors,” Professor Medcalf said.

“Unexpectedly, we found that the process of t-PA inactivation by one of its natural inhibitors actually contributed to brain injury, because it leads to the activation of MMP-3.

“Now we know that if we block MMP-3 with an inhibitor, we can protect the brain following TBI,” Professor Medcalf said.

“We now have a new and promising therapeutic target for the treatment of human TBI, which has not, so far, been significantly improved by pharmacological intervention,” Professor Rosenfeld said.

The Traumatic Brain Injury Attorneys of Reeves, Aiken & Hightower

If you or someone you know have been injured or killed by a traumatic brain injury, seek help from an experienced brain injury attorney like those at  Reeves, Aiken & Hightower.  Call us at 877-374-5999, or contact us at this link, to schedule a free, private consultation.  We can help you evaluate your claim and get you the recovery you deserve.

Concussions as Much of a Problem in College Football as in High School

The American Orthopedic Society for Sports Medicine now reports that college football players are receiving brain injuries at similar rates to high school players.  Until recently, the focus on brain injury in sports has rested solidly on high school football injuries.  Now a study by this orthopedic society shows that concussions are increasing amongst the service academies players.

This information is all the more shocking due to the nature of the game played by the service academies.  Recently, the service academies tend to play schedules dominated by teams that would seem to allow the schools less severe collisions between helmets.  The severity of injury must be expected to be greater in the power conferences where the collisions between helmets would be more forceful causing greater injuries.

It may however be that the service academies face a greater risk of head injury due to the schedules they play.  The schedules tend to be split between games where they are heavily overmatched by power conference teams and games where they are on a level playing field with their conference colleagues.  The result may be that being unprepared for rougher play they are more apt to receive severe head injury.

Luckily, most head injuries in college football are not very severe, mostly concussions. The number of reports of brain injury at the services academies was 23 in the 2009 season and 42 in the 2010 season, which should be alarming given the total number of players involved was around 450.

The Brain Injury Attorneys of Reeves, Aiken & Hightower

If you or someone you know have been injured or killed by a traumatic brain injury, seek help from an experienced brain injury attorney like those at  Reeves, Aiken & Hightower. Review our credentials, make sure we are right for you, and call us at 877-374-5999, or contact us at this link, to schedule a free, private consultation.  We can help you evaluate your claim and get you the recovery you deserve.

Anosmia, Loss of Sense of Smell, a Result of Traumatic Brain Injury – SC NC Brain Injury Attorney

Anosmia, or the loss of one’s sense of smell is an oddball disorder, but is surprisingly common.  The loss of the critical sense of smell would seemingly be more likely to be caused by a brain disorder or sinus problems can be caused by traumatic brain injury. Traumatic brain injury is in fact the cause in 30% of the cases of anosmia.  Who knew?

A simple concussion can be sufficient to trigger the severing of the olfactory nerves causing a total loss of the sense of smell.  Obviously, traumatic brain injury would be enough to cause it as well.

Other possible causes are the results of either surgical accident or negligent brain surgery.

Traumatic Brain Injury Attorneys

If you think you or someone you know have suffered a brain injury, seek medical help immediately.  Then seek the counsel of experienced brain injury attorneys like those at Reeves, Aiken, & Hightower.  We know how to fight for you and your family in serious brain injury cases.  Compare our credentials to any other law firm. Then call 877-374-5999 or contact us at this link for a private consultation.

Existing Diabetes Drug Minimizes Damage from Traumatic Brain Injury – Brain Injury Lawyer

Traumatic brain injury (TBI) doesn’t cause as many fatalities as some other forms of traumatic injury, but it does cause affect brain function for a lifetime.   Not to mention the cumulative cost of a lifetime of more expensive medical treatment.

Now though, research shows that an existing diabetes drug can be used to keep the effects of traumatic brain injury (TBI) from worsening.  This is certainly good news for sufferers of traumatic brain injury (TBI) accidents.  The drug is already approved for treatment of diabetes.  Although it was originally designed to keep diabetes in check, and although it is effective in that role, it has already been found affect at protecting the brain against the ravages of certain brain disorders, like Alzheimer’s.

As always though, there is more research to be done.  Although this drug is effective in theory, to bring it into full effectiveness against the results of traumatic brain injury (TBI) accidents, its dosage and combination with other drugs will have to be worked out.

Traumatic Brain Injury Attorneys

If you think you or someone you know have suffered a brain injury, seek medical help immediately.  Then seek the counsel of experienced brain injury attorneys like those at Reeves, Aiken, & Hightower.  We know how to fight for you and your family in serious brain injury cases.  Compare our credentials to any other law firm. Then call 877-374-5999 or contact us at this link for a private consultation. Don’t worry. We are here for you.

For more information about this drug research click here.